Postdoctoral Research Fellow
Department of Neurology and Neurological Sciences
Dr. Kacie Deters received her PhD in Medical Neuroscience from Indiana University in 2017 using neuroimaging and genetics to characterize neural characteristics of tauopathies, including Alzheimer’s disease (AD). She then began her postdoctoral research career at Stanford where her primary research interests are studying ethnic/racial disparities of AD specific risk factors on cognitive performance in older adults.
SAGE Project: APOE, neuropathology, and cognitive decline in Blacks
Decline in cognitive function can be detected years before AD sets in, however most studies are focused on non-Hispanic Whites. Although some variation is observed, many studies suggest several racial disparities in aging and dementia risk factors exist between non-Hispanic Blacks and Whites. For example, APOE4 is the largest genetic risk factor for AD in non-Hispanic Whites, yet the effect on AD risk is reduced in non-Hispanic Blacks. The goal of this study is to understand how race and genetic ancestry impact the association of AD genetic risk factors and neuropathology on cognitive decline.