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Longevity & Healthy Aging Research Consortium

Longevity & Healthy Aging Research Consortium

Longevity & Healthy Aging Research Center

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News and Accomplishments

KALW Public Radio Bay Area: The Stanford Letter Project helps you discuss your end-of-life wishes

Although 92 percent of US adults say it’s important to discuss their end-of-life care wishes, only 32 percent have had this conversation, and less than one-third have advanced-care directives in place. These discussions are crucial to ensure your wishes. The Stanford Letter Project gives you the tools to ensure you and your loved ones are prepared. 

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Epigenetics Biomarker of Post Operative Delirium and Long Term Cognitive Decline among Elderly Dementia Patients

Dr. Gen Shinozaki from Stanford Psychiatry has received a grant from the National Institute on Aging to investigate epigenetic biomarkers related to post-operative delirium and long-term cognitive decline in elderly patients, both with and without dementia. Delirium, particularly common after surgery in elderly patients, is a serious condition that can lead to cognitive deterioration and even death, especially for those with Alzheimer’s or dementia. Despite its severity, predicting and detecting delirium remains a major challenge.

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Fiji’s Ambassador to the United States gave an Award of Honor to Dr. Lloyd Minor and Dr. VJ Periyakoil

Honor Award and Celebration July 2024: Stanford Medicine’s Longevity and Healthy Aging consortium had a wonderful annual celebration on 7/31/2024. His Excellency Ratu Ilisoni Vuidreketi, Fiji’s Ambassador to the United States of America was the Chief Guest.  Dr. Lloyd Minor, Dean of Stanford University School of Medicine was the keynote speaker. 

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Dr. VJ Periyakoil received the 2024 Visionary Award by the American Academy of Hospice and Palliative Medicine (AAHPM)
Dr. VJ Periyakoil

Dr. VJ Periyakoil, Professor of Medicine and Associate Dean of Research, received the 2024 Visionary Award by the American Academy of Hospice and Palliative Medicine (AAHPM). Every five years, AAHPM calls upon its extensive membership of over 5,000 professionals to nominate visionaries who have significantly shaped the landscape of palliative care. “This program recognizes extraordinary individuals who continue to enhance the delivery of care for seriously ill patients and have brought true innovation to our field,” noted Wendy-Jo Toyama, MBA FASAE, AAHPM CEO. Dr. Periyakoil’s groundbreaking contributions at Stanford University and her tireless efforts in advancing the field have earned her this distinguished accolade.

Machine learning prediction of mild cognitive impairment and its progression to Alzheimer’s disease

Health Science Report 2023: Effective screening for mild cognitive impairment (MCI) as a risk factor for developing Alzheimer’s disease is a crucial step in helping aging population with their needs Early detection and automated screening for MCI and dementia could offer opportunities for deliberate study and recruitment into trials for developing other potentially useful therapeutics or interventions. The study results were published in October, 2023.

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Targeting repetitive laboratory testing with electronic health records-embedded predictive decision support: A pre-implementation study

March, 2023: Dr. Jonathan Chen’s lab recently published  “Targeting repetitive laboratory testing with electronic health records: a pre-implementation study” in Clinical Biochemistry with funding from the SAGE Pilot Award Program.

Exploratory studies of microbiome in healthy human aging

October, 2022: Dr. Xin Zhou’s recent work, “Exploratory studies of oral and fecal microbiome in healthy human aging”, was published in Frontiers in Aging.  https://pubmed.ncbi.nlm.nih.gov/36338834/

Award for Inclusion Research

Dr. Juan Banda’s lab was recently awarded the 2022 Google Research Award for the project “Towards more equitable representation of Latin American Spanish natural language processing resources for social media mining of health-related applications”.

Stanford Researchers Named to Clinical Research Forum Top Ten List

March 2022: Dr. James Zou, Lead of the SAGE Center Methods Core, has received the Clinical Research Forum 2022 Top Ten Clinical Research Achievement Award in recognition of his study, “Evaluating eligibility criteria of oncology trials using real-world data and AI,” the results of which were published in Nature last year.

The study focused on using data science and artificial intelligence (AI) to design clinical trials, with a specific focus on making clinical trials more inclusive. “Trials frequently have pages and pages of eligibility criteria, which filters out a significant number of patients who would otherwise gain access to the latest treatments,” explained Dr. Zou. “These restrictions can also lead to the exclusion of female, minority, and older patients.”

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Stanford Cardiovascular Institute Recognition Award

Dr. Ngan Huang was recently awarded the 2022 CVI Recognition Award for her efforts leading and providing educational opportunities for CVI members and active participation in numerous activities that strengthen the CVI community.

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Next-Generation Artificial Intelligence for Diagnosis: From Predicting Diagnostic Labels to "Wayfinding"

Julia Adler-Milstein, PhD1; Jonathan H. Chen, MD, PhD; Gurpreet Dhaliwal, MD

Improving the diagnostic process is a quality and safety priority.With the digitization of health records and rapid expansion of health data, the cognitive demand on the diagnostician has increased. The use of artificial intelligence (AI) to assist human cognition has the potential to reduce this demand and associated diagnostic errors. However, current AI tools have not realized this potential, due in part to the long-standing focus of these tools on predicting final diagnostic labels instead of helping clinicians navigate the dynamic refinement process of diagnosis. This Viewpoint highlights the importance of shifting the role of diagnostic AI from predicting labels to “wayfinding” (interpreting context and providing cues that guide the diagnostician).